It was announced on October 22nd that the third season of the TV anime " The Apothecary Diaries ," based on the light novel by Natsu Hyuga , which originated on the novel submission website " Shosetsuka ni Naro, " and a feature film will be produced. This will be the first time that a feature film version of " The Apothecary Diaries" will be produced. The third season of the TV anime will be split into two seasons, with the first season airing on Nippon Television in October 2026 and the second in April 2027. The story moves from the harem to the common people, with signs of a disaster threatening the country, a Jinshi as the emperor's younger brother, and new challenges await Maomao and Jinshi. Continuing from the second season, the series will be directed by Fudesaka Akinori.
The film version will be released in December 2026. It is a completely new story with the original story concept by the original author, Natsu Hyuga, who was the series composition and director for the first season of the TV anime and the series composition and general director for the second season. A super teaser visual has also been released, featuring an impressive look of determination in Maomao's eyes. Something like a flame is drawn around Maomao, along with the tagline, "A supreme mystery flickers in her eyes."
The original author , Natsu Hyuga , commented, "At the end of the second season, it was announced that a sequel had been decided. I'm sure everyone was wondering whether there would be a third season of the TV anime or a movie. It turns out that it will be both. The Apothecary anime is also celebrating its second anniversary, and I think that's thanks to all the fans and everyone who has supported it. In order to meet everyone's expectations, we are producing both the third season and the movie. The third season has a completely different atmosphere from the second season. I'm working hard together with the production side to make it even more enjoyable than the first and second seasons. I only helped out with the third season, but I worked hard on the movie. It's a completely new story. I wrote it. I wrote it. It's a story that has never been published online or in books. There is also a lot of other fun information. I look forward to having fun with you all again, so please look forward to it."
Aoi Yuki , who plays Maomao, said, "I hope to be able to continue weaving this world for a long time, just like the works of my predecessors, so I would like to continue to play the role with care. Not only that, there's even a movie version!? And it's a completely original story written by the author!? Something incredible has fallen from the sky...! I am really, really looking forward to it! I would be grateful if you would recommend ' The Apothecary Diaries ' to those around you while you wait for the release!"
Takeo Otsuka , who plays Jinshi, said, "Right after the second season finished airing, it was announced that a sequel would be made, and now there's a third season and a movie! I'm looking forward to seeing what kind of stories will unfold in each season and what Maomao and Jinshi will do! There's lots of fun things to come. Let's continue enjoying ' The Apothecary Diaries' together!"
In response to fans' requests to "definitely see it at the cinema!", it was also announced that a retrospective theatrical screening of the first and second seasons will be held. Starting on February 15, 2026, six episodes will be screened every other week in five cities across the country. Yuki, who plays Maomao, Otsuka, who plays Jinshi, and Takuya Kirimoto, who plays Jinshi, will appear on stage for the first season on February 15, while Yuki, Otsuka, and Asami Seto, who plays Zisui/Rouran, will appear on stage for the second season on April 12.
It has also been revealed that the "The Apothecary Diaries " exhibition, which began in Tokyo in March 2025, will travel to cities across Asia. It will start in Hong Kong in November, and then travel to mainland China, Bangkok, Kuala Lumpur, and other cities. Visuals exclusive to the Asia exhibition have also been released.
It has also been announced that in addition to Yuuki and Otsuka, Katsuyuki Konishi, who plays Gao Shun, Atsumi Tanezaki, who plays Princess Tamaba, Seto, Misaki Kuno, who plays Katsuyuki Konishi, Atsumi Tanezaki , who plays Ma Sen, and Toshiyuki Toyonaga, who plays Toshiyuki Toyonaga , will appear at the series' The Apothecary Diaries ' Special Event - Summer Garden Misaki Kuno 2026," which will be held at the National Hall of Pacifico Yokohama (Nishi-ku, Yokohama) on August 15, 2026.
A promotional video commemorating the second anniversary of the anime's broadcast, "Anime ' The Apothecary Diaries' 2nd Anniversary PV," has also been released on YouTube. Starting with Maomao's famous line, "This is poison," the video looks back on the first and second seasons, and plays past opening themes such as "Hana ni Natte" by Ryokuoushoku Shakai, "Ambivalent" by Uru, "Hyakka Ryoran" by Rira Ikuta, and "Kusushiki" by Mrs. Green Apple.
The light novel version of "The Apothecary Diaries" is published by Hero Bunko (Imagica Infos), and its comic adaptation has also gained popularity. The total number of copies of the original series has exceeded 40 million. The story is set in the glamorous harem of a certain continent, where Maomao, a poison taster, and the handsome harem manager, Jinshi, become embroiled in an incident that unfolds in a harem filled with conspiracies and rumors.
The first season of the TV anime aired from October 2023 to March 2024, and the second season from January to July 2025. The series has gained popularity, having been selected as the grand prize winner in the "TikTok First Half Trend Awards 2025," which announces the most popular content and keywords on TikTok in the first half of 2025.
