It has been announced that a sequel to the anime " The Apothecary Diaries, " based on the light novel by Natsu Hyuga , which was born from the novel posting site " Shosetsuka ni Naro, " will be produced. The second season of the TV anime aired its final episode on July 4, and the production of the sequel was announced. A super teaser PV for the sequel was also released on YouTube.
The trailer begins with a scene where Jinshi receives a letter from Rouran at the fortress, and includes scenes and keywords that hint at the sequel, along with the words of Maomao and Jinshi. A wheat field is also shown, along with the words "The stage is moving to a new land."
Original author Natsu Hyuga commented, "I am very grateful that a sequel has been decided. However, the first and second seasons were originally intended to be the length of four novels. And now the sequel...I am feeling a lot of pressure to make the content more interesting. I will continue to check if there is anything missing from the story and support the anime team as much as I can. The series is still going strong, so I hope everyone will look forward to it."
Aoi Yuki , who plays the main character Maomao, said, "I felt very sad when filming for the second season finished, so I'm incredibly happy about the sequel! I'm also happy to be able to announce the sequel at this timing, which surely erases the sadness of having such an epic story come to an end. Everyone involved in every section of ' The Apothecary Diaries ' has a strong love for the work, and they prepare it carefully before delivering it to everyone's homes, so you may have to wait a little longer for the sequel, but I hear that there are plenty of measures in place to keep you enthusiastic and supported in the meantime, so I hope you will continue to support us!"
Takeo Otsuka , who plays Jinshi, said, "Thank you to everyone who watched until the final episode of the second season. And it has been decided that a sequel will be made! Congratulations! Thank you! I'm very happy that we will still be able to watch and act in the world of ' The Apothecary Diaries' in the anime. There seem to be lots of fun things happening until the sequel is broadcast, so I hope you will continue to support us, including those!"
The light novel version of "The Apothecary Diaries" is published by Hero Bunko (Imagine Infos), and its comic adaptation is also gaining popularity. The original series has sold over 40 million copies in total. Set in the glamorous harem of a certain continent, the story follows Maomao, a poison taster girl, and Jinshi, the handsome harem manager, as they get caught up in an incident that occurs in the harem, which is full of conspiracies and rumors. The first season of the TV anime aired on Nippon TV from October 2023 to March 2024. The second season began airing on Nippon TV's anime slot "FRIDAY ANIME NIGHT" on January 10, and the final episode, episode 48, "The Beginning," aired on July 4.
The second season was always ranked highly on various distribution platforms, and related words trended on social media before and after the TV anime aired, creating a lot of excitement. In the "Anime and Manga Awards that Fans Are Passionate About," announced in May, it won both the currently airing anime category and the theme song category. It also attracted attention when it won the grand prize and the manga and anime category award in the "TikTok First Half Trend Awards 2025."
